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NAFDAC urges Stakeholders to lead vigilance on Antimicrobial Resistance, Adverse Drug Reactions

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The National Agency for Food and Drug Administration and Control (NAFDAC) has called on stakeholders and Nigerians to lead vigilance against Antimicrobial Resistance (AMR) to medicines/drugs and Adverse Drug Reactions (ADR).

The Director-General of NAFDAC, Prof. Mojisola Adeyeye, made the call on during a one-day Pharmacovigilance Workshop and Stakeholders Town Hall Meeting in Enugu.

Represented by NAFDAC’s Director, South-East Zone, Dr Festus Ukadike, the director-general noted that the gravest consequences of irrational medicine use today is AMR.

She explained that the misuse and overuse of antibiotics had accelerated the emergence of resistant microorganisms that no longer respond to conventional treatment.

“This means that infections previously treatable with common antibiotics are becoming increasingly difficult and expensive to manage.

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“If urgent action is not taken, antimicrobial resistance may reverse decades of medical progress and place humanity at serious risk.

“This is why Pharmacovigilance is extremely important. Pharmacovigilance refers to the science and activities relating to the detection, assessment, understanding, and prevention of adverse effects or any other medicine-related problems.

“In simple terms, Pharmacovigilance helps us ensure that medicines remain safe and effective even after they have been approved and released into the market,” she said.

Adeyeye noted that no medicine is completely free from side effects.

“However, through effective Pharmacovigilance systems, healthcare professionals and patients can identify harmful reactions early, report them appropriately, and help regulatory authorities take necessary actions to protect the public,” she said.

She said that Pharmacovigilance remained a core mandate of the agency, adding that stakeholders and general public should play active part in monitoring AMR and ADR to ensure effectiveness of medicine and treatment.

Speaking, the Chairman, Enugu State Traditional Rulers’ Council, Igwe Samuel Asadu, commended NAFDAC for the workshop, while urging the agency to put more effort in curbing sales of fake medicines in the hinterlands.

Asadu said that Pharmacovigilance was needed more in the hinterlands of the state to stop people paddling fake medicines and “selling outright chalk as medicine in villages in the state”.

He gave the commitment of royal fathers in the state in providing necessary support to NAFDAC to check paddlers of fake medicines, “as we see our people die due to their activities.”

Corroborating, the State Coordinator of World Health Organization (WHO), Dr Adaeze Ugwu, said that the organisation would continue to support NAFDAC in the agency’s resolve to strengthen food and healthcare in the country.

Also, Dr Oliver Ezemba, Chairman, Nigerian Association of Patent and Proprietory Medicine Dealers (NAPPMED), urged everybody to get concerned on the issues of AMR and ADR to guarantee quality medicines for everyone.

Ezemba called on Nigerians to imbibe the habit of reporting any irregularities observed while using a medicine to NAFDAC for proper investigation, which would serve the benefit of many Nigerians using same medicine.

The participants asked questions on AMR and ADR as well as made pledge on reporting any suspectable AMR or ADR case through the NAFDAC’s Med Safety Mobile App using their cellphone or computer set.

In the workshop, a presentation was made on “Need for Effective Pharmacovigilance by All’, delivered by Mr Chidi Uche and Mrs Ogechi Udeh, who are NAFDAC officials.

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154 students hospitalised over suspected drug reaction in Katsina

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One hundred and fifty-four students of Government Science Secondary School, Batagarawa, Katsina State, were hospitalised following a suspected adverse reaction to praziquantel tablets administered to treat bilharzia.

The incident occurred on Monday, according to a statement issued on Wednesday by the Katsina State Police Command’s Public Relations Officer, Abubakar Sadiq Aliyu.

Aliyu said the students reportedly developed symptoms of an adverse drug reaction after receiving the tablets from the school authorities.

Praziquantel is used to treat schistosomiasis, also known as bilharzia, a parasitic disease associated with contact with freshwater contaminated by the parasites.

The police spokesman said the affected students were taken to hospital for treatment, with no casualties or deaths recorded.

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He added that the remaining 25 students, who had been kept in hospital for further medical attention, had also been treated and discharged.

According to him, all the affected students were in good health and had been reunited with their families and schoolmates.

The Commissioner of Police, Ali Umar Fage, thanked members of the public for their cooperation and calmness during the incident.

He urged residents to refrain from spreading unverified reports and rumours, assuring them that the command would continue to protect lives and property across the state.

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Poisonous Drinks: Ondo Govt confirms 49 deaths, 170 affected as new cases are recorded

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• Eight deaths recorded in Irele LG

The Ondo State Government has confirmed more deaths in connection with the consumption of suspected poisonous alcoholic drinks in Odigbo Local Government Area.

The Commissioner for Health, Banji Ajaka, told journalists on Wednesday in Akure, the state capital, that 49 fatalities have now been reported, as against 39 reported last week.

The government also said the cases increased from 60 to 170 as of last Friday.

Mr Ajaka said some incidents have been reported in the Irele Local Government Area, with eight fatalities recorded in the area.

The Health Commissioner for Health, while giving an update on the situation, said that health authorities were intensifying surveillance, case management and contact tracing to contain the outbreak and identify the source of the poisonous substance.

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He expressed concern that while eight of the deaths were recorded in Irele, the overall number of people affected across the areas by the incident has risen to 170.

He said the government was yet to relent in its efforts to establish the source of the substance, adding that investigators were examining whether the poisoning originated from a single source or multiple sources.

According to Ajaka, teams had been deployed to the affected communities to monitor the situation, manage cases and trace the source of the suspected poisonous substance.

He said the state government was also working with security and regulatory agencies, including the National Agency for Food and Drug Administration and Control, National Drug Law Enforcement Agency, Department of State Services, Nigeria Security and Civil Defence Corps and other relevant agencies.

Ajaka said the matter was discussed at a national meeting involving commissioners for health across the country and officials of the Nigeria Centre for Disease Control and Prevention, where Ondo State’s rapid response in surveillance, case management and tracking was commended.

He said the government would continue its investigation until the source of the poisoning was established.

The latest figures came after the commissioner had earlier disclosed that 29 people had died in connection with the suspected poisoning in Odigbo Local Government Area, with 121 persons affected at that stage.

Ajaka had linked the Odigbo outbreak to locally produced alcoholic and alcoholic-herbal substances consumed during two naming ceremonies in the affected communities.

He said investigations showed that an individual who was not a member of one of the families hosting a naming ceremony procured the substance and brought it to the event for guests to consume.

The affected communities previously identified in Odigbo include New Town, Odole, Okele, Orita Odigbo, Araromi-Obu and Oniparaga.

Following the outbreak, the state government banned the production and sale of locally brewed alcoholic and alcoholic-herbal beverages in Odigbo Local Government Area as a precautionary measure.

The commissioner also confirmed the arrest of a suspect in Araromi-Obu in connection with the production and distribution of the substances.

Ajaka warned residents against consuming unregulated alcoholic and herbal preparations, stressing that substances promoted for medicinal purposes could also pose serious health risks if their contents were unknown or unregulated.

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My wife had headaches from oranges preserved with chemicals – Osinbajo

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Former Vice President, Yemi Osinbajo with his wife, Dolapo
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Former Vice-President Yemi Osinbajo has raised concerns over the use of dangerous chemicals in ripening and preserving fruits, recounting how a laboratory test found his wife’s freshly squeezed orange juice “not fit for human consumption”.

Osinbajo spoke at the Open Day for Gardeners’ Seminar themed “Leaving the Earth Better Than We Found It”, held in Lagos on August 28, with a video of the event shared on his YouTube channel on Wednesday.

Osinbajo said his wife, Dolapo, developed frequent headaches after she began drinking freshly squeezed orange juice every day.

“Dolly, my dear wife, likes to have a full glass of freshly squeezed orange juice every day, a very healthy habit, by the way, especially since she stopped consuming any form of carbonated drinks many years ago,” he said.

“But then after a while she started having some strange headaches drinking her fresh juice every day. Then she checked everything she was eating and drinking, and we were wondering what could the cause of this be?”

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He said they initially ruled out the orange juice because it was considered a healthy drink.

“We assumed, of course, it couldn’t be the ‘healthy’ orange juice,” he said.

“The results came back. It showed the orange juice, freshly squeezed, was not fit for human consumption.”

Osinbajo attributed the result to the use of harmful chemicals by some farmers and fruit sellers, warning that the problem could expose Nigerians to health risks.

His words, “Apparently farmers use dangerous pesticides for fruits and vegetables, and fruit and vegetable sellers use very dangerous chemicals sometimes to ripen or preserve fruits and vegetables.”

“Calcium carbide is used very frequently to force fruits such as bananas, mangoes, pawpaws and tomatoes to change colour and look ripe very quickly,” Osinbajo added.

The former vice-president cited studies from different parts of the country which he said had documented the use of chemicals among some fruit sellers.

He referenced a 2024 study in Ado-Ekiti, Ekiti State, where, according to him, half of 20 fruit sellers interviewed admitted using calcium carbide. Similarly, another study in Uyo, Akwa Ibom State, where 25 per cent of fruit sellers reportedly admitted to using the chemical to ripen fruits.

Osinbajo further referred to a 2023 survey in Lagos, saying 22 out of 50 fruit retailers admitted using chemicals to preserve their produce.

“These were the ones who agreed they do,” he said.

His call comes amid growing concerns over the proliferation of counterfeit and substandard products in Nigeria, with NAFDAC and SON facing increased pressure as Nigerians use social media to expose food, drugs, cosmetics and other consumer goods suspected to be dangerous.

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