
International
Penis cancer on the rise, resulting in 6,500 amputations in Brazil

“I started visiting medical clinics to find out what it was, but all the doctors told me it was due to excess skin and prescribed medication,” the 63-year-old recalls.
Despite the medication, the wart continued to grow. It started to take a toll on his marriage and João and his wife’s sex life declined. “We were like siblings,” he admits. He was determined to find out what was going on.
For five years João, not his real name, went back and forth to specialists who prescribed more medication and ordered new biopsies. “Nothing solved it,” he says.
Then, in 2023, he was given a diagnosis – João had penile cancer.
“For my family, it was a very unpleasant surprise, even more so because I had to have part of the penis amputated. I feel like I was decapitated,” he says.
“It’s a type of cancer that you can’t talk about with people because it could turn into a joke.”
Penile cancer is rare, but incidences and mortality rates are on the rise around the world.
According to the latest studies, Brazil, where João is from, has one of the highest incidence rates of 2.1 per 100,000 men.
‘Terrified of surgery’
Between 2012 and 2022, there were 21,000 reported cases, according to Brazil’s Ministry of Health. This resulted in more than 4,000 deaths and, over the past decade, there have been more than 6,500 amputations – averaging one every two days.
Maranhão, the poorest state in Brazil, was found to have the highest incidence rate globally at 6.1 per 100,000 men.
Symptoms of penile cancer often start with a sore on the penis that does not heal and a strong-smelling discharge. Some people get bleeding and colour changes of the penis, too.
When detected early, there is a high chance of recovery through treatments such as the surgical removal of the lesion, radiotherapy and chemotherapy.
But if left untreated, partial or total amputation of the penis, and possibly other nearby genital organs such as the testicles, may become necessary.
João underwent a partial amputation in January and says it was a difficult time.
“It’s something you never imagine will happen to you, and when it does, you can’t just go around telling people,” he says.
“I was terrified of surgery, but there was no other alternative. The feeling in the first weeks after the surgery was one of sadness, I can’t deny it. Not having part of your penis is horrible.”
Some patients undergo a total amputation which is life-changing.
Thiago Camelo Mourão from the Department of Urology at AC Camargo Cancer Center in São Paulo says: “In the case of partial amputation, urine continues to exit through the penis.
“However, in total amputation, the urethral orifice can be relocated to the perineum, between the scrotum and the anus, requiring the patient to urinate while sitting on the toilet.”
Mauricio Dener Cordeiro of the Brazilian Society of Urology says the persistent infection of human papillomavirus (HPV), a name given to a common group of viruses, is “one of the main risk factors”. HPV can be transmitted during sex and in some cases, it can lead to cancers including in the mouth and penis.
He says: “Mass vaccination against HPV is essential due to its high effectiveness in preventing related lesions,” but he adds that vaccination rates in Brazil are below the level needed to be truly effective.
“In Brazil, despite the availability of the vaccine, the HPV vaccination rate remains low for girls – reaching only 57% – and for boys, it doesn’t exceed 40%,” he says. “The ideal coverage to prevent the disease is 90%.”
He believes misinformation about the vaccine, unfounded doubts about its effectiveness and a lack of vaccination campaigns have contributed to the low take-up.
According to the UK’s National Health Service (NHS) website, smoking can increase the risk of getting penile cancer, too. It also says you might be more likely to get penile cancer if you “have problems pulling back your foreskin (the skin covering your penis) to keep your penis clean (a condition called phimosis)”.
“When a man does not expose the glans and fails to clean the foreskin properly, it produces a secretion that accumulates,” Dr Cordeiro says. “This creates a highly favourable environment for bacterial infections.
“If this occurs repeatedly, it becomes a risk factor for the appearance of the tumour.”
But Brazil is not the only place where penile cancer is on the rise. According to the latest research, the number of cases is increasing around the world.
In 2022, the journal JMIR Public Health and Surveillance published the results of a large-scale analysis involving the latest data from 43 countries.
It found the highest incidence of penile cancer between 2008 and 2012 was in Uganda (2.2 per 100,000), followed by Brazil (2.1 per 100,000) and Thailand (1.4 per 100,000). The lowest was in Kuwait (0.1 per 100,000).
“Although developing countries still bear the higher incidence and mortality of penile cancer, the incidence is on the rise in most European countries,” the team of researchers led by Leiwen Fu and Tian Tian from Sun Yat-Sen University in China found.
They reported that England had seen an increase in penile cancer, rising from 1.1 to 1.3 per 100,000 between 1979 and 2009 and in Germany cases increased by 50% from 1.2 to 1.8 per 100,000 between 1961 and 2012.
These figures are only set to get higher, according to the Global Cancer Registries prediction tool. It estimates that by 2050, the global incidence of penile cancer will rise by more than 77%.
This change can largely be attributed to the ageing population, according to the experts, who say the highest incidence occurred in men in their 60s.
Dr Cordeiro says: “Penile cancer is a rare disease but also highly preventable”.
He advised that using condoms during sex and undergoing surgery to remove the foreskin in cases of phimosis could help reduce the risk of penile cancer.
Neil Barber, Clinical Lead for Urology at Frimley Health NHS Foundation Trust, adds: “Penile cancer is almost unheard of in the circumcised population. Poor hygiene and infections beneath the foreskin, as well as conditions like phimosis that make it difficult to retract the foreskin and maintain good hygiene, are risk factors. This is linked to higher overall infection risks”.
“Established risk factors also include unprotected sex, specifically not using condoms, with poor hygiene further increasing risks through this route.”
João is currently waiting for his latest test results, which he will receive later this year. “I’m confident that these exams will show that I’ll be cured,” he says.
“Now, following the amputation, the pain has gone away, and I’ve been feeling much better. But I’ll have to live with a partially amputated penis for the rest of my days.”
According to Cancer Research UK, more than 90% of men diagnosed with penile cancer which has not spread to nearby lymph nodes survive for five years or more. (BBC)
International
59 burnt to death, 155 others injured during hip-hop concert tragedy


A fire tore through an overcrowded nightclub packed with mostly young people in North Macedonia early Sunday, killing 59 people, apparently after on-stage fireworks at a hip-hop concert set the venue ablaze, authorities said.
Some 155 people who were injured in the inferno had been taken to hospitals across the country, 22 of them in critical condition, officials said. Some of the more serious cases were taken to hospitals in other European countries.
Interior Minister Pance Toskovski said that more than 20 wounded and three of those killed in the fire were minors.
“At the time of the event around 500 people were inside, while 250 tickets were sold,” he said.
The blaze started in the Club Pulse in the eastern town of Kocani, which was packed with mostly young fans attending a concert by a popular hip-hop duo called DNK.
“The fire started around 2:30 am (0130 GMT), the sparklers that were on stage ignited the styrofoam on the ceiling. I heard an explosion and the roof collapsed,” one young person who was inside for the concert told local media.
“We all rushed to get out, we all ran towards one door that was for both entry and exit,” they were quoted as saying.
Another, a young woman waiting outside a hospital in the capital Skopje for a friend being treated for burns, said: “Initially we didn’t believe there was a fire. Then there was huge panic in the crowd and a stampede to get out.”
The fire was probably caused by pyrotechnic devices “used for lighting effects at the concert,” said Toskovski, who visited the scene with Prime Minister Hristijan Mickoski.
“Sparks caught the ceiling, which was made of easily flammable material, after which the fire rapidly spread across the whole discotheque, creating thick smoke,” Toskovski said.
At a later press conference Toskovski said that the authorities were investigating whether “corruption” and “bribery” were linked to the deadly nightclub fire.
“This company does not have a legal license for work,” he said, referring to the club.
“This license, as many other things in Macedonia in the past, is connected with bribery and corruption. In this case, those involved in illegal issuance of license have names and will be held responsible,” he added.
More than 20 people were under investigation over the blaze, 15 of whom were in police custody, while others were in hospital, he said.
Among the suspects are the two members of the band, an owner of the club and organisers, among others.
A former director of the rescue services and a state secretary at the economy ministry were among those detained, he said.
The head of the Kocani hospital, Kristina Serafimovska, told media that “most of the dead unfortunately suffered injuries from the stampede that occurred in the panic while trying to exit”.
“Seventy of the patients have burns and carbon monoxide poisoning,” she said.
One of the members of the DNK duo that had performed, Vladimir Blazev, had burns to his face and needed assistance breathing, his sister told local media outlets.
– ‘Very sad day’ –
“This is a difficult and very sad day” for the country, Mickoski wrote on his Facebook account. “The loss of so many young lives is irreparable, and the grief of their families, their loved ones and their friends is immeasurable.”
The government proclaimed a seven-day mourning period and ordered flags lowered.
“A decision will also be made on an urgent and extraordinary inspection of all nightclubs, discotheques and restaurants that organise parties,” the government said in a statement.
Pope Francis sent prayers to the victims and survivors and wished “the families of the dead, mostly young people, the expression of his deep condolence,” the Vatican said in a message addressed to the bishop of Skopje, Kiro Stojanov.
Videos posted on social networks and shot before the fire showed there were “stage fountains” set up — a type of indoor fireworks used during performances.
Other videos published by media showed huge flames emerging from the building, a two-storey white structure in Kocani, a town with 30,000 residents.
An AFP photographer in the town saw military medical vehicles arrive to reinforce staff at the local hospital tending to some of the injured.
As the day unfolded, the leaders of neighbouring countries sent condolences.
Many of the patients in serious condition were transferred to other countries like Bulgaria, Greece, Serbia and Turkey.
The EU’s foreign policy chief, Kaja Kallas, said on X that she was “deeply saddened about the tragic fire” and that “the EU shares the grief and pain of the people of North Macedonia”. (AFP)
International
Man commits suicide after killing his two sons over ‘poor academic performance’


A 31-year-old Indian accountant, Vanapalli Chandra Kishore, committed suicide after k!lling his two sons, aged six and seven, over their poor academic performance.
Kishore left a suicide note stating that he realised his two children, who were in upper kindergarten (UKG) and class I, are not doing well academically and would struggle to establish themselves in a highly competitive world.
The gruesome incident happened at Ramanayyapet, in Kakinada town of Andhra Pradesh, on Friday night, March 14, 2025.
Sarpavaram police station inspector B Peddi Raju said Kishore worked as an assistant at the ONGC office, an oil company in Kakinada.
“He killed his two sons by tying up their hands and legs and drowning them in two buckets of water. The family is financially stable, so his actions are surprising,” the police officer added.
Kishore had married Tanuja Sai Rani in 2017 and the couple had two sons, Joshith (7) and Nikhil (6), who studied in a nearby private school.
Their neighbours said they found the couple to be normal and friendly. As the children were not doing well at school, the parents had decided to shift them to a better school from the new academic year and also made enquiries.
As Friday was a holiday for Holi, Kishore along with his wife and children had gone to the ONGC office at Vakalapudi village, in Kakinada rural mandal, to celebrate the festival with his colleagues.
A few minutes after reaching there, he told his wife that he would take the children to a tailor to get new school uniforms stitched. He left her in the office and went out with the children.
When they didn’t return for a long time, she called her husband on his mobile repeatedly, but he did not respond.
After some time, Kishore sent a message that he would be back in 10 minutes. But he did not return.
A worried Tanuja, along with one of his colleagues, went to their house and found the doors closed from inside.
When there was no response from inside even after loud knocks and calls, Kishore’s colleague called some locals and broke open the main door.
While Kishore was found hanging from the ceiling fan in one of the rooms, Joshith and Nikhil were found dead in the bathroom.
Their hands and legs were tied and their heads were dumped in buckets full of water.
“How the kids aged six and seven, in UKG and class 1, will fare in the real world cannot be judged so early. We are not sure what their father thought. There could be other reasons why Kishore took this extreme step,” a police officer stated on Saturday.
“We came to know that the kids had joined a new school recently and they were not coping well with the change, We are investigating all angles.”
Police are questioning Kishore’s wife and also seeking information from relatives who live in the same locality
International
Son beats parents to death with cinder block


A suspect in Mississippi was arrested after police said he beat his parents to death with a cinder block.
Police in Pascagoula said 39-year-old Darold Sim Payne was arrested after a four-hour standoff with law enforcement after he barricaded himself inside his home.
The Jackson County Coroner identified the victims as the suspect’s father and mother, 86-year-old Harold Payne and 72-year-old Jittuan Payne.
The coroner confirmed the couple both died of blunt force trauma.
Wednesday afternoon, officers responded to the home in response to a report of a fight in the front yard.
When officers arrived on the scene, they saw a man, later identified as Darold Payne, run into the house and barricade himself.
Officers from multiple agencies worked to contain the scene.
After attempts to negotiate with Payne, officers deployed tear gas into the home, which eventually caused him to surrender. He was then taken into custody.
Officials later confirmed two people, identified as Payne’s parents, dead outside of the home.
Pascagoula Police Chief Terry Scott said the parents and son lived together in the house. He doesn’t believe anyone else lived there.
Chief Scott praised the work of his team, along with the other law enforcement agencies that responded.
“We did everything we could to protect his life and get him into custody without hurting any officers or anyone else,” Scott said.
The double homicide case is being handled by the Pascagoula Police Department’s Criminal Investigations Division.
The victims’ autopsies will take place Friday.
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